ATUX-1215

ATUX-1215 is an activator of protein phosphatase 2A (PP2A). ATUX-1215 reduced the phosphorylation of ERK, p38, JNK, and Akt and the secretion of IL-12p70, GM-CSF, and IL1α in Bleomycin hydrochloride-treated animals. ATUX-1215 can slow the progression of lung fibrosis.


Cat. No.: EX-A13155	Purity: >98%

	Chemical structure of ATUX-1215

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	590	In-stock
25mg	998	In-stock
50mg	1380	In-stock
100mg	1850	In-stock

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CAS No.	2910929-53-0
Purity	>98%
Formula	C27H24F5NO4S
Mol Weight	553.541
Color	White to off-white
State	Solid
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Meshach Pillai, et al. Small-Molecule Activation of Protein Phosphatase 2A Counters Bleomycin-Induced Fibrosis in Mice. 2023. [2]. Nazam N, et al., PP2A activation overcomes leptomeningeal dissemination in group 3 medulloblastoma. J Biol Chem. 2024 Nov;300(11):107892.
CoA	CoA of ATUX-1215

Smiles:	O=S(NC1CC(OCC1)C2C3=CC=C(F)C=C3CCC4=CC(F)=CC=C42)(C5=CC=C(C=C5)OC(F)(F)F)=O


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