ATRN-119

ATRN-119 is a water soluble orally bioavailable ATM- and Rad3-related protein kinase (ATR) inhibitor for potential use in cancer research. Demonstrates high potency with $IC_{50}$ values below 20 nM (specifically, around 4 nM in some studies).


Cat. No.: EX-A10372	Purity: >98%

	Chemical structure of ATRN-119

For research only, Do not use for Human!

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Synonyms	ATRN 119
CAS No.	2762168-00-1
Purity	>98%

Reference:	[1].Methods of treating DNA double-strand break-capturing nuclear envelope tubules (dsbNETs) associated diseases using dsbNETs modulators Role: Pharmacological Activity, Therapeutic Use Patent Number: CA3237512 Publication Date: 2026-03-01 [2].combination therapies with DNA damage response inhibitors and [ 177Lu]Lu-PSMA-617 Role: Pharmacological Activity, Therapeutic Use Patent Number: WO2025210599 Publication Date: 2025-10-09 [3].Methods and systems for treating disease using an ATR/CHEK1 signaling pathway inhibitor Role: Pharmacological Activity, Therapeutic Use Patent Number: WO2025151786
CoA	CoA of ATRN-119


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