ATF3-IN-1

ATF3-IN-1 is a ferroptosis and ATF3 inhibitor. ATF3-IN-1 inhibits oxidative stress and ferroptosis through the ATF3/SLC7A11/GPX4 pathway, exerting anti-ischemic stroke effects. ATF3-IN-1 can attenuate ischemia/reperfusion (I/R) injury and improve neuronal survival. ATF3-IN-1 has neuroprotective effects and can be used to study ischemic stroke.


Cat. No.: EX-A17093	Purity: >98%

	Chemical structure of ATF3-IN-1

For research only, Do not use for Human!

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CAS No.	2952703-90-9
Purity	>98%
Formula	C24H37NO7
Mol Weight	451.5531
Color	Light yellow to yellow
State	Solid
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C 3 years, 4°C 2 years; In solvent -20°C, 1 month.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Kong X, et al. Discovery of a potential anti-ischemic stroke agent by suppressing ferroptosis through the ATF3/SLC7A11/GPX4 pathway. Eur J Med Chem. 2025 Oct 15;296:117873.
CoA	CoA of ATF3-IN-1

Smiles:	O=C(N1CCOCC1)OCCCCCCCCCCC2=C(C)C(C(OC)=C(OC)C2=O)=O


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