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Product Information:

AS2863619

AS2863619 is a potent, orally active cyclin-dependent kinase 8 (CDK8) and CDK19 inhibitor with IC50s of 0.61 nM and 4.28 nM, respectively.

Cat. No.: EX-A7116    Purity: >98%
Chemical
Chemical structure of AS2863619


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg385In-stock
50mg600In-stock
100mg850In-stock
200mg1250In-stock
500mg1950In-stock
1g2950In-stock


CAS No.2241300-51-4
Purity>98%
FormulaC16H14Cl2N8O
Mol Weight405.241
ColorWhite to off-white
Statesolid powder
SolubilitySoluble in DMSO 250 mg/mL H2O? 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Akamatsu M, et al. Conversion of antigen-specific effector/memory T cells into Foxp3-expressing Treg cells by inhibition of CDK8/19. Sci Immunol. 2019 Oct 25;4(40). pii: eaaw2707.

CoACoA of AS2863619

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