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Product Information:

ARS-1630

ARS-1630, a less active enantiomer of ARS-1620, is a novel inhibitor of mutant K-ras G12C extracted from patent WO 2015054572 A1.

Cat. No.: EX-A2714    Purity: >98%
Chemical
Chemical structure of ARS-1630


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg438in_stock
1g982in_stock
2g1669in_stock
5g3687in_stock


SynonymsARS-1630 (R enantiomer)
CAS No.1698055-86-5
Purity>98%
FormulaC21H17ClF2N4O2
Mol Weight430.835
Colorwhite to yellow
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Liansheng Li, et al. Inhibitors of kras g12c. WO 2015054572 A1.

[2]. Janes MR, et al. Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor. Cell. 2018 Jan 25;172(3):578-589.e17.

CoACoA of ARS-1630
Smiles:OC1=C(C(F)=CC=C1)C1=C(F)C2=NC=NC(N3CCN(CC3)C(=O)C=C)=C2C=C1Cl

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