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Product Information:

ARN726

ARN726 is a potent NAAA (N-acylethanolamine acid amidase) inhibitor with an IC50 of 0.073 µM. ARN726 decreases alcohol self-administration in a dose-dependent manner.

Cat. No.: EX-A9417    Purity: >98%
Chemical
Chemical structure of ARN726


For research only, Do not use for Human!

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CAS No.1628343-77-0
Purity>98%
FormulaC14H24N2O3
Mol Weight268.352
ColorWhite to off-white
StateSolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years, 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Fotio Y, et al. N-acylethanolamine acid amidase (NAAA) inhibition decreases the motivation for alcohol in Marchigian Sardinian alcohol-preferring rats. Psychopharmacology (Berl). 2021 Jan;238(1):249-258.

[2]. Petracca R, et al. Novel activity-based probes for N-acylethanolamine acid amidase. Chem Commun (Camb). 2017 Aug 22;53(86):11810-11813.

CoACoA of ARN726
Smiles:O=C(OCCCCC1CCCCC1)N[C@@H]2C(NC2)=O

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