ARN19689

ARN19689 is a potent, selective, orally active and non-covalent inhibitor of N Acylethanolamine-Hydrolyzing Acid Amidase (NAAA), with an IC50 of 42 nM. ARN19689 is a promising pharmacological tool to be further investigated in the field of inflammatory conditions.


Cat. No.: EX-A12910	Purity: >98%

	Chemical structure of ARN19689

For research only, Do not use for Human!

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CAS No.	2320521-34-2
Purity	>98%
Formula	C19H27N5O4S
Mol Weight	421.514
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Di Fruscia P, et al. Discovery and SAR Evolution of Pyrazole Azabicyclo[3.2.1]octane Sulfonamides as a Novel Class of Non-Covalent N-Acylethanolamine-Hydrolyzing Acid Amidase (NAAA) Inhibitors for Oral Administration. J Med Chem. 2021 Sep 23;64(18):13327-13355.
CoA	CoA of ARN19689

Smiles:	S(=O)(=O)(N1[C@@]2(C[C@@H](OC=3C=NC(COCC)=CN3)C[C@]1(CC2)[H])[H])C=4C(C)=NNC4C


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