Arimoclomol maleate

Arimoclomol maleate (BRX-220) is a co-inducer of heat shock proteins (HSP). Arimoclomol protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system.


Cat. No.: EX-A8534A	Purity: >98%

	Chemical structure of Arimoclomol maleate

For research only, Do not use for Human!

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Synonyms	BRX-220
CAS No.	289893-26-1
Purity	>98%
Formula	C18H24ClN3O7
Mol Weight	429.852
Color	White to light yellow
State	solid powder
Solubility	DMSO : 250 mg/mL H2O : 100 mg/mL
Shelf Life	>1 years if stored properly
Storage	4°C, sealed storage, away from moisture
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Rakonczay Z Jr, et al. Nontoxic heat shock protein coinducer BRX-220 protects against acute pancreatitis in rats. Free Radic Biol Med. 2002 Jun 15;32(12):1283-92. [2]. Phukan J. Arimoclomol, a coinducer of heat shock proteins for the potential treatment of amyotrophic lateral sclerosis. IDrugs. 2010 Jul;13(7):482-96.
CoA	CoA of Arimoclomol maleate

Smiles:	C1CCN(CC1)C[C@H](CO/N=C(/C2=C[N+](=CC=C2)[O-])\Cl)O.C(=C\C(=O)O)\C(=O)O


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