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Product Information:

ARD-2128

ARD-2128 is a highly potent, orally bioavailable PROTAC androgen receptor (AR) degrader. ARD-2128 has the potential for the research of the prostate cance.

Cat. No.: EX-A5711    Purity: >98%
Chemical
Chemical structure of ARD-2128


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
5mg421in_stock
10mg617in_stock
25mg952in_stock
50mg1252in_stock
100mg1714in_stock
250mg2525in_stock


CAS No.2222111-87-5
Purity>98%
FormulaC45H50ClN7O6
Mol Weight820.375
ColorLight yellow to green yellow
Statesolid powder
SolubilitySoluble in DMSO 100 mg/mL
Shelf Life>2 years if stored properly
Storage-20℃, sealed storage, away from moisture and light In solvent :-20℃, 1 month (sealed storage, away from moisture and light)
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Han X, et al. Strategies toward Discovery of Potent and Orally Bioavailable Proteolysis Targeting Chimera Degraders of Androgen Receptor for the Treatment of Prostate Cancer [published online ahead of print, 2021 Aug 25]. J Med Chem. 2021;10.1021/acs.jmed

CoACoA of ARD-2128
Smiles:O=C(C1=CC=C(C=C1)N2CCN(CC2)CC3CCN(CC3)C4=CC5=C(C=C4)C(N(C5=O)C(C(N6)=O)CCC6=O)=O)N[C@H]7C(C)([C@@H](C7(C)C)OC8=CC=C(C(Cl)=C8)C#N)C

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