AR-13503

AR-13503 (AR-13324 M1 metabolite) is the hydrolytic metabolite of AR-13324 mesylate. AR-13324 is a ROCK kinase and PKC inhibitor with anti-angiogenic and retinal health-improving effects, showing potential for use in retinal disease research.


Cat. No.: EX-A10925	Purity: >98%

	Chemical structure of AR-13503

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	720	In-stock
50mg	1080	In-stock
100mg	1620	In-stock
250mg	3180	In-stock

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Synonyms	AR-13324 M1 metabolite
CAS No.	2309668-15-1
Purity	>98%
Formula	C19H19N3O2
Mol Weight	321.3731
Color	Off-white to light yellow
State	Solid
Solubility	DMSO : 40 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years; 4℃, 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Ding J, et al. ROCK/PKC inhibitor AR-13503 inhibits angiogenesis and protects the barrier function of retinal pigment epithelium[J]. Investigative Ophthalmology & Visual Science, 2018, 59(9): 205-205. [2]. Carbajal K, et al. AR-13503 Enhances the efficacy of aflibercept in a mouse model of proliferative diabetic retinopathy[J]. Investigative Ophthalmology & Visual Science, 2018, 59(9): 200-200. [3]. Halasz E, et al. AR-13503, a ROCK inhibitor, reduces rod axon retraction during retinal detachment[J]. Investigative Ophthalmology & Visual Science, 2018, 59(9): 4221-4221.
CoA	CoA of AR-13503

Smiles:	OCC1=CC=C([C@@H](CN)C(NC2=CC(C=CN=C3)=C3C=C2)=O)C=C1


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