APP-018

APP-018 (D-4F) is 18 D-amino acids peptide that mimics apolipoprotein A-I (apoA-I). APP-018 improves the anti-inflammatory activity of high-density lipoprotein (HDL). APP-018 can be used in researches of cardiovascular diseases.


Cat. No.: EX-A13011	Purity: >98%

	Chemical structure of APP-018

For research only, Do not use for Human!

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CAS No.	452782-06-8
Purity	>98%
Formula	C114H156N24O28
Mol Weight	2310.6023
Color	White to off-white
State	Solid
Solubility	DMSO : 50 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -80°C, 2 years , -20°C, 1 year; sealed storage, away from moisture. In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Bloedon LT, et al., Safety, pharmacokinetics, and pharmacodynamics of oral apoA-I mimetic peptide D-4F in high-risk cardiovascular patients. J Lipid Res. 2008 Jun;49(6):1344-52.
CoA	CoA of APP-018

Smiles:	C([C@H](C(N[C@H](CC1=CC=CC=C1)C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@H](CC2=CC=C(O)C=C2)C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@H](CC3=CC=CC=C3)C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@H](CC4=CC=CC=C4)C(N)=O)=O)C)=O)CCC(O)=O)=O)CCCCN)=O)


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