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Apoptosis inducer 56

Apoptosis inducer 56 is an apoptosis inducer. Apoptosis inducer 56 induces DNA damage (upregulation of γH2AX and p-ATM expression) by minor groove binding. Apoptosis inducer 56 induces intrinsic apoptosis (upregulation of p53 and Bax/Bcl-2 ratio, cleaved caspase-7) via S-phase cell cycle arrest. Apoptosis inducer 56 shows selectivity for cancer cells over normal breast epithelial cells. Apoptosis inducer 56 can be used for the research of breast cancer .

Cat. No.: EX-A16759    Purity: >98%
Chemical
Chemical structure of Apoptosis inducer 56


For research only, Do not use for Human!

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CAS No.952306-31-9
Purity>98%
FormulaC11H17N3O3S
Mol Weight271.336
 
 
Reference:  

[1].Das T, et al. A thiazole-based hydroxamic acid derivative induces mitochondrial apoptosis and S-phase arrest in MCF-7 cells via DNA minor groove binding. Bioorg Chem. 2026;170:109460.

CoACoA of Apoptosis inducer 56
Smiles:O=C(CCCCCCC(NO)=O)NC1=NC=CS1

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