AP1189

Resomelagon (AP1189) acetate is a potent, orally active melanocortin receptor (MR) agonist about MC1 and MC3. Resomelagon acetate induces ERK1/2 phosphorylation and Ca2+ mobilization.


Cat. No.: EX-A9366	Purity: >98%

	Chemical structure of AP1189

For research only, Do not use for Human!

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Synonyms	Resomelagon
Synonyms 2	AP1189 acetate
CAS No.	959850-74-9
Purity	>98%
Formula	C16H18N6O4
Mol Weight	358.3519
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Montero-Melendez T, Gobbetti T, Cooray SN, Jonassen TE, Perretti M. Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects. J Immunol. 2015 Apr 1;194(7):3381-8. doi: 10.4049/jimmunol.1402645. Epub 2015 Feb 27. PubMed PMID: 25725103.
CoA	CoA of AP1189

Smiles:	NC(N/N=C/C=C/C1=CC=CN1C2=CC=CC=C2[N+]([O-])=O)=N.CC(O)=O


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