AP-C5

AP-C5 displays selective inhibition of guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 7.2, which can be used for the research of diarrheal disease[1]. AP-C5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.


Cat. No.: EX-A14601	Purity: >98%

	Chemical structure of AP-C5

For research only, Do not use for Human!

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CAS No.	2234272-10-5
Purity	>98%
Formula	C16H13N5
Mol Weight	275.3079
Color	Light yellow to light brown
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃, 3 years; 4℃, 2 years; In solvent -20℃, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293(21):8173-8181.
CoA	CoA of AP-C5

Smiles:	C#CCNC1=NC=CC(=N1)C2=CC=C(C=C2)N3C=CN=C3


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