Antroquinonol

Antroquinonol is a ubiquinone derivative from Antrodia camphorata with anti-inflammatory and anticancer activities.Antroquinonol reduces oxidative stress and inhibits inflammation and sclerosis in mice with focal segmental glomerulosclerosis through enhancement of the Nrf2 signaling pathway.Antroquinonol has potential for use in the treatment of non-small cell lung cancer. Antroquinonol has potential for the treatment of non-small cell lung cancer and may be used in colon cancer research.


Cat. No.: EX-A8166	Purity: >98%

	Chemical structure of Antroquinonol

For research only, Do not use for Human!

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Synonyms	(+)-Antroquinonol
CAS No.	1010081-09-0
Purity	>98%
Formula	C24H38O4
Mol Weight	390.5561
Color	White to off-white
State	solid powder
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Yi, Zhen-Wei et al. “Antrodin A from mycelium of Antrodia camphorata alleviates acute alcoholic liver injury and modulates intestinal flora dysbiosis in mice.” Journal of ethnopharmacology vol. 254 (2020): 112681. doi:10.1016/j.jep.2020.112681 [2]. Lin, Hsien-Chun et al. “Antroquinonol, a Ubiquinone Derivative from the Mushroom Antrodia camphorata, Inhibits Colon Cancer Stem Cell-like Properties: Insights into the Molecular Mechanism and Inhibitory Targets.” Journal of agricultural and food chemistry vol. 65,1 (2017): 51-59. doi:10.1021/acs.jafc.6b04101 [3]. Tsai, Pei-Yi et al. “Antroquinonol reduces oxidative stress by enhancing the Nrf2 signaling pathway and inhibits inflammation and sclerosis in focal segmental glomerulosclerosis mice.” Free radical biology & medicine vol. 50,11 (2011): 1503-16. doi:10.1016/j.freeradbiomed.2011.02.029 [4]. Ho, Ching-Liang et al. “Antroquinonol blocks Ras and Rho signaling via the inhibition of protein isoprenyltransferase activity in cancer cells.” Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol. 68,8 (2014): 1007-14. doi:10.1016/j.biopha.2014.09.008
CoA	CoA of Antroquinonol

Smiles:	O=C1C(OC)=C(OC)[C@H](O)[C@H](C/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)[C@H]1C


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