Antifungal agent 122

Antifungal agent 122 (compound 201) is a potent and broad-spectrum antifungal agent. Antifungal agent 122 prevents fungal phase transition and the formation of fungal biofilm. Antifungal agent 122 inhibits CYP3A4-M and CYP3A4-T enzyme activity with IC50 values of 2.11, 4.53 µM. Antifungal agent 122 shows no cytotoxicity.


Cat. No.: EX-A12810	Purity: >98%

	Chemical structure of Antifungal agent 122

For research only, Do not use for Human!

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CAS No.	3054212-80-2
Purity	>98%
Formula	C28H24F4N4O
Mol Weight	508.51
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Sun Y, et al. Discovery of highly potent triazole derivatives with broad-spectrum antifungal activity based on Iodiconazole. Eur J Med Chem. 2024 Oct 9;280:116949.
CoA	CoA of Antifungal agent 122

Smiles:	FC1=CC=C([C@@]([C@H](N(C)CC2=CC=C(C#CC3=CC=C(F)C=C3F)C=C2)C)(O)CN4N=CN=C4)C(F)=C1


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