Anti-inflammatory agent 102

Anti-inflammatory agent 102 (Compound 11a) is an orally active anti-inflammatory agent. Anti-inflammatory agent 102 exerts its anti-inflammatory effect by blocking the activation of the ASK1/p38 MAPKs/NF-κB signaling pathway. Anti-inflammatory agent 102 has significant anti-inflammatory activity and can inhibit the release of NO, ROS, and inflammatory factors (such as IL-6, TNF-α, IL-1β). Anti-inflammatory agent 102 can be used in the study of inflammatory diseases such as ulcerative colitis (UC).


Cat. No.: EX-A13004	Purity: >98%

	Chemical structure of Anti-inflammatory agent 102

For research only, Do not use for Human!

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CAS No.	3053104-47-2
Purity	>98%
Formula	C16H16ClN3O3
Mol Weight	333.77
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Juan Zhang, et al. Discovery of novel N-(5-chloro-2,4-dimethoxyphenyl)-N-heterocyclic ketone analogs as potent anti-inflammatory agents against ulcerative colitis. Bioorganic Chemistry, Volume 161, 2025, 108576, ISSN 0045-2068.
CoA	CoA of Anti-inflammatory agent 102

Smiles:	O=C1N(C2=NC=CC=C2)CCN1C3=CC(Cl)=C(OC)C=C3OC


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