Angiotensin (1-7)

Angiotensin 1-7 is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity (IC50=0.65 μM). Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity.


Cat. No.: EX-A7295	Purity: >98%

	Chemical structure of Angiotensin (1-7)

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	650	In-stock
1g	985	In-stock
2g	1500	In-stock
5g	2500	In-stock
10g	3800	In-stock

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CAS No.	51833-78-4
Purity	>98%
Formula	C41H62N12O11
Mol Weight	899.0048
Color	White to off-white
State	solid powder
Solubility	H2O : ? 30.2 mg/mL (33.59 mM)
Shelf Life	>2 years if stored properly
Storage	Powder -80℃ 2 years; -20℃ 1 year; In solvent -80℃ 6 months; -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Gómez-Mendoza DP, et al. Angiotensin-(1-7) oral treatment after experimental myocardial infarction leads to downregulation of CXCR4. J Proteomics. 2019;208:103486. [2]. Li P, et al. Angiotensin-(1-7) augments bradykinin-induced vasodilation by competing with ACE and releasing nitric oxide. Hypertension. 1997 Jan;29(1 Pt 2):394-400. [3]. Khajah MA, et al. Anti-Inflammatory Action of Angiotensin 1-7 in Experimental Colitis. PLoS One. 2016 Mar 10;11(3):e0150861. [4]. Alzayadneh EM, et al. Angiotensin-(1-7) abolishes AGE-induced cellular hypertrophy and myofibroblast transformation via inhibition of ERK1/2. Cell Signal. 2014 Sep 19. pii: S0898-6568(14)00314-3.
CoA	CoA of Angiotensin (1-7)


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