background


Product Information:

AMG-925

AMG 925 is a potent, selective, and orally available FLT3/CDK4 dual inhibitor with IC50s of 2±1 nM and 3±1 nM, respectively.

Cat. No.: EX-A9264    Purity: >98%
Chemical
Chemical structure of AMG-925


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
1gget quoteInquire


SynonymsFLX 925
CAS No.1401033-86-0
Purity>98%
FormulaC26H29N7O2
Mol Weight471.5542
ColorOff-white to light yellow
StateSolid
SolubilitySoluble in DMSO/H2O
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years, 4℃ 2 years; In solvent -20℃ 1 year;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Keegan K, et al. Preclinical evaluation of AMG 925, a FLT3/CDK4 dual kinase inhibitor for treating acute myeloid leukemia. Mol Cancer Ther. 2014 Apr;13(4):880-9.

CoACoA of AMG-925
Smiles:N(C=1N=C2N(C=3C(C2=CN1)=CC=NC3)[C@H]4CC[C@H](C)CC4)C=5N=C6C(=CC5)CN(C(CO)=O)CC6

KEYWORDS: buy AMG-925 | AMG-925 supplier | purchase | cost | manufacturer | order | distributor | buy 1401033-86-0 | 1401033-86-0 supplier