Inhibitor Specialist 
Product Information:
| Cat. No.: EX-A3538 | Purity: >99% |
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| Chemical structure of AMG-510 |
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| Synonyms | AMG510 |
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| Synonyms 2 | Sotorasib |
| CAS No. | 2296729-00-3 |
| Purity | >99% |
| Formula | C30H30F2N6O3 |
| Mol Weight | 560.5944 |
| State | solid powder |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
| Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Reference: | [1]. Marwan Fakih, et al, Phase 1 study evaluating the safety, tolerability, pharmacokinetics (PK), and efficacy of AMG 510, a novel small molecule KRASG12Cinhibitor, in advanced solid tumors. Journal of Clinical Oncology. |
| CoA | CoA of AMG-510 |
| Smiles: | O=C(C=C)N1C[C@H](C)N(C2=NC(N(C3=C(C)C=CN=C3C(C)C)C4=C2C=C(F)C(C5=C(O)C=CC=C5F)=N4)=O)CC1 |
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