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Product Information:

alpha-Amanitin

α-Amanitin is the principal toxin of several deadly poisonous mushrooms, exerting its toxic function by inhibiting RNA-polymerase II.

Cat. No.: EX-A6231    Purity: >98%
Chemical
Chemical structure of alpha-Amanitin


For research only, Do not use for Human!

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Synonymsα-Amanitin
Synonyms 2α-Amanitine
CAS No.23109-05-9
Purity>98%
FormulaC39H54N10O14S
Mol Weight918.97
ColorOff-white to light brown
Statesolid powder
SolubilitySoluble in DMSO 100 mg/mL H2O 100 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20°C, protect from light.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Zhao J, et al. Pathological effects of the mushroom toxin alpha-amanitin on BALB/c mice. Peptides. 2006 Dec;27(12):3047-3052.

[2]. Kume K, et al. α-Amanitin Restrains Cancer Relapse from Drug-Tolerant Cell Subpopulations via TAF15. Sci Rep. 2016 May 16;6:25895

[3]. Kaya E, et al. Evaluation and comparison of alpha- and beta-amanitin toxicity on MCF-7 cell line. Turk J Med Sci. 2014;44(5):728-32

[4]. Park MW, et al. RNA Polymerase II Inhibitor, α-Amanitin, Affects Gene Expression for Gap Junctions and Metabolic Capabilities of Cumulus Cells, but Not Oocyte, during in vitro Mouse Oocyte Maturation. Dev Reprod. 2013 Mar;17(1):63-72

CoACoA of alpha-Amanitin

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