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Product Information:

AKV-9

AKV-9 (also known as NU-9) is an analog of the cyclohexane‑1,3‑dione family of compounds and a protein aggregation inhibitor.

Cat. No.: EX-A10124    Purity: >98%
Chemical
Chemical structure of AKV-9


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg250In-stock
500mg365In-stock
1g500In-stock
2g800In-stock
3g960In-stock
5g1280In-stock


SynonymsAKV9
Synonyms 2NU-9
CAS No.1307262-15-2
Purity>98%
FormulaC16H14F6O3
Mol Weight368.271
Statesolid
Solubilitysoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃ 2 years, protect from light; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Genç, Barış et al. “NU-9 improves health of hSOD1G93A mouse upper motor neurons in vitro, especially in combination with riluzole or edaravone.” Scientific reports vol. 12,1 5383. 30 Mar. 2022, doi:10.1038/s41598-022-09332-4

[2]. Zhang, Yinan et al. “Chiral cyclohexane 1,3-diones as inhibitors of mutant SOD1-dependent protein aggregation for the treatment of ALS.” ACS medicinal chemistry letters vol. 3,7 (2012): 584-587. doi:10.1021/ml3000963

CoACoA of AKV-9
Smiles:C[C@@H](C1CC(=O)CC(=O)C1)OC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F

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