Akt Inhibitor XI

FPA-124, a cell-permeable copper complex, is a selective Akt inhibitor with an IC50 of 0.1 μM. FPA-124 interacts with both the pleckstrin homology (PH) and the kinase domains of Akt. FPA-124 induces apoptosis.


Cat. No.: EX-A14251	Purity: >98%

	Chemical structure of Akt Inhibitor XI

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	580	In-stock
500mg	880	In-stock
1g	1280	In-stock

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CAS No.	902779-59-3
Purity	>98%
Formula	C11H9Cl2CuN3O2S
Mol Weight	381.725
Color	Light green to green
State	Solid
Solubility	DMSO : 5 mg/mL H2O : < 0.1 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years; In solvent -20°C, 1 month.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Barve V, et al. Synthesis, molecular characterization, and biological activity of novel synthetic derivatives of chromen-4-one in human cancer cells. J Med Chem. 2006 Jun 29;49(13):3800-8. [2]. Biscetti F, et al. Pioglitazone enhances collateral blood flow in ischemic hindlimb of diabetic mice through an Akt-dependent VEGF-mediated mechanism, regardless of PPARgamma stimulation. Cardiovasc Diabetol. 2009 Sep 8;8:49.
CoA	CoA of Akt Inhibitor XI

Smiles:	C1=CC=C2C(=C1)C(=O)C(=CO2)/C=N\NC(=S)N.Cl[Cu]Cl


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