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Product Information:

AKR1B1/STAT3/SLC7A11-regulator-1

AKR1B1/STAT3/SLC7A11-regulator-1 (5a) is an AKR1B1/STAT3/SLC7A11 regulator that reverses DOX resistance in MCF-7/ADR cells by enhancing ferroptosis activity. AKR1B1/STAT3/SLC7A11-regulator-1 can be used in breast cancer research.

Cat. No.: EX-A13280    Purity: >98%
Chemical
Chemical structure of AKR1B1/STAT3/SLC7A11-regulator-1


For research only, Do not use for Human!

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Purity>98%
FormulaC28H32N4O5
Mol Weight504.5775
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Zhang C, et al. Novel bis-pocket binding aldose reductase inhibitors sensitize MCF-7/ADR cells to doxorubicin in a dual-role manner. Bioorg Chem. 2025 Apr;157:108286.

CoACoA of AKR1B1/STAT3/SLC7A11-regulator-1
Smiles:CC(N[C@@H](C(NC1CCC(CC1)NC(/C(C#N)=C/C2=CC=C(C=C2)O)=O)=O)COCC3=CC=CC=C3)=O

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