AK-1690

AK-1690 is a potent and selective STAT6 PROTAC degrader. AK-1690 reduces the levels of STAT6 protein in cells (DC50=1 nM) and depletes STAT6 protein in mouse tissues. AK-1690 can be used for the research of cancer.


Cat. No.: EX-A10611	Purity: >98%

	Chemical structure of AK-1690

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	712	In-stock
50mg	985	In-stock
100mg	1585	In-stock
250mg	2550	In-stock

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CAS No.	2984505-88-4
Purity	>98%
Formula	C51H56F2N5O11PS
Mol Weight	1016.053
Color	white to off-white
State	solid powder
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃ 2 years, protect from light, stored under nitrogen, 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Kaneshige A, et, al. Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader. J Med Chem. 2024 Sep 23.
Data Sheet	Data sheet of AK-1690
CoA	CoA of AK-1690
SDS	SDS of AK-1690

Smiles:	C(#CCCCCCO[C@H]1C[C@@H](C(=O)N2C[C@H](OCC2)C3=CC=CC=C3)N(C([C@@H](NC(=O)C4=CC=5C(S4)=CC=C(C(P(=O)(O)O)(F)F)C5)[C@@](C)(C)C)=O)C1)C6=C7C(C(=O)N(C7)C8C(=O)NC(=O)CC8)=CC=C6


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