Afoxolaner

Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions , resulting in excess neuronal stimulation and death of the arthropod.


Cat. No.: EX-A3267	Purity: >99%

	Chemical structure of Afoxolaner

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	350	In-stock
250mg	550	In-stock
1g	850	In-stock
5g	1550	In-stock
10g	2350	In-stock

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CAS No.	1093861-60-9
Purity	>99%
Formula	C26H17ClF9N3O3
Mol Weight	625.87
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Mitchell EB, et al. Efficacy of afoxolaner against Ixodes scapularis ticks in dogs.Vet Parasitol. 2014 Apr 2;201(3-4):223-5. [2]. Beugnet F, et al. Afoxolaner against fleas: immediate efficacy and resultant mortality after short exposure on dogs.Parasite. 2014;21:42.
CoA	CoA of Afoxolaner

Smiles:	O=C(C1=C2C=CC=CC2=C(C3=NOC(C(F)(F)F)(C4=CC(C(F)(F)F)=CC(Cl)=C4)C3)C=C1)NCC(NCC(F)(F)F)=O


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