Afabicin disodium

Afabicin (Debio 1450) is the proagent of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci.


Cat. No.: EX-A9305	Purity: >98%

	Chemical structure of Afabicin disodium

For research only, Do not use for Human!

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Synonyms	Debio 1450 disodium
Synonyms 2	AFN-1720 disodium
CAS No.	1518800-29-7
Purity	>98%
Formula	C23H22N3Na2O7P
Mol Weight	529.39
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Flamm RK, et al. Activity of Debio1452, a FabI inhibitor with potent activity against Staphylococcus aureus and coagulase-negative Staphylococcus spp., including multidrug-resistant strains. Antimicrob Agents Chemother. 2015;59(5):2583-2587.
CoA	CoA of Afabicin disodium

Smiles:	O=P(O[Na])(O[Na])OCN1C2=NC=C(/C=C/C(N(C)CC(OC3=CC=CC=C43)=C4C)=O)C=C2CCC1=O


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