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Product Information:

AEP-IN-1

AEP-IN-1 (Compound 13e) is a CNS agent-like non-covalent inhibitor of asparagine endopeptidase (AEP), with the IC50 of 89 nM. AEP-IN-1 can be used for the research of numerous neurological diseases such as Alzheimer’s disease (AD).

Cat. No.: EX-A14017    Purity: >98%
Chemical
Chemical structure of AEP-IN-1


For research only, Do not use for Human!

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CAS No.3032742-75-6
Purity>98%
FormulaC18H27N3O3
Mol Weight333.4253
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lorenzo Calugi, et al. Modular synthesis of 2,4-diaminoanilines as CNS drug-like non-covalent inhibitors of asparagine endopeptidase. Bioorg Med Chem. 2022 Jun 1;63:116746.

CoACoA of AEP-IN-1
Smiles:O=C(C1CCN(C2=CC(N3CCOCC3)=CC=C2N)CC1)OCC

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