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Product Information:

Adriforant

PF-3893787 (also known as Adriforant; ZPL-3893787; PF-3893787 and ZPL-389) is a novel and potent histamine H4 receptor antagonist with Ki of 2.4 nM and it is also a functional antagonist with Ki of 1.56 nM. Adriforant shows an excellent in vitro profile that warrants their further investigation in relevant models of human disease.

Cat. No.: EX-A7358    Purity: >98%
Chemical
Chemical structure of Adriforant


For research only, Do not use for Human!

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SynonymsPF 3893787
CAS No.943057-12-3
Purity>98%
FormulaC13H22N6
Mol Weight262.354
ColorWhite to off-white
Statesolid powder
SolubilityH2O : 100 mg/mL DMSO : ? 83.33 mg/mL
Storage4°C, sealed storage, away from moisture and light In solvent : -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1].Mowbray CE, et al. Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: a novel histamine H4 receptor antagonist. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6596-602.

CoACoA of Adriforant

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