ADH-503

ADH-503 is an orally active and allosteric CD11b agonist. ADH-503 leads to the repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhances dendritic cell responses.


Cat. No.: EX-A5679	Purity: >98%

	Chemical structure of ADH-503

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	350	In-stock
200mg	550	In-stock
500mg	850	In-stock
1g	1285	In-stock

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Synonyms	(Z)-Leukadherin-1 choline
CAS No.	2055362-74-6
Purity	>98%
Formula	C27H28N2O5S2
Mol Weight	524.652
Color	Brown to reddish brown
State	solid powder
Solubility	Soluble in DMSO 21.43 mg/mL Methanol 100 mg/mL Ethanol 3.33 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Panni RZ, et al. Agonism of CD11b reprograms innate immunity to sensitize pancreatic cancer to immunotherapies. Sci Transl Med. 2019 Jul 3;11(499).
CoA	CoA of ADH-503


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