AD-8007

AD-8007 is an acetyl CoA synthase 2 (ACSS2) inhibitor that can cross the blood-brain barrier. AD-8007 can significantly reduce lipid storage and cell colony formation in vitro models, and increase tumor cell death. AD-8007 has anti-cancer activity and can be used in the research of breast cancer.


Cat. No.: EX-A10180	Purity: >98%

	Chemical structure of AD-8007

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	785	In-stock
250mg	1185	In-stock
500mg	1685	In-stock
1g	2385	In-stock
5g	get quote

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Synonyms	Compound 6q
CAS No.	1497439-74-3
Purity	>98%
Formula	C22H26N2O
Mol Weight	334.4546
Color	white to off-white
State	solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Esquea E, et al. Discovery of novel brain permeable human ACSS2 inhibitors for blocking breast cancer brain metastatic growth. bioRxiv [Preprint]. 2023 Dec 23:2023.12.22.573073. [2]. Esquea E,et al. Discovery of novel brain permeable human ACSS2 inhibitors for blocking breast cancer brain metastatic growth. bioRxiv [Preprint]. 2023 Dec 23:2023.12.22.573073.
CoA	CoA of AD-8007

Smiles:	O=C([C@@H](N)C1CC1)N2CC(C3=CC=CC=C3)(C4=CC=CC=C4)CCC2


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