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Product Information:

AD 2900

AD 2900 (AD2900, AD-2900) is a novel potent, broad S1P receptor antagonist with IC50 of 3.8, 3.2, 6.2, 5.9 and 0.405 uM for S1P1, 2, 3, 4 and 5 respectively.

Cat. No.: EX-A7188    Purity: >95%
Chemical
Chemical structure of AD 2900


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg350In-stock
25mg685In-stock


CAS No.18360-29-7
Purity>95%
FormulaC20H43NO3
Mol Weight345.5603
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Song, Jing et al. “The novel sphingosine-1-phosphate receptors antagonist AD2900 affects lymphocyte activation and inhibits T-cell entry into the lymph nodes.” Oncotarget vol. 8,32 53563-53580. 27 Jun. 2017

[2]. Dagan, Arie et al. “Synthetic, non-natural sphingolipid analogs inhibit the biosynthesis of cellular sphingolipids, elevate ceramide and induce apoptotic cell death.” Biochimica et biophysica acta vol. 1633,3 (2003): 161-9.

CoACoA of AD 2900

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