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Product Information:

Acumapimod

Acumapimod (BCT197) is an orally active p38 MAP kinase inhibitor, with an IC50 of less than 1 μM for p38α.

Cat. No.: EX-A1450    Purity: >98%
Chemical
Chemical structure of Acumapimod


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg450In-stock
500mg700In-stock
1g1150In-stock
2g1950In-stock
5g3550In-stock


SynonymsBCT-197
CAS No.836683-15-9
Purity>98%
FormulaC22H19N5O2
Mol Weight385.4186
Statesolid powder
Solubilitysoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Norman P, et al. Investigational p38 inhibitors for the treatment of chronic obstructive pulmonary disease. Expert Opin Investig Drugs. 2015 Mar;24(3):383-92.

[2]. De Buck S, et al. Population PK-PD Model for Tolerance Evaluation to the p38 MAP Kinase Inhibitor BCT197. CPT Pharmacometrics Syst Pharmacol. 2015 Dec;4(12):691-700.

CoACoA of Acumapimod
Smiles:CC1=C(C=C(C=C1)C(=O)NC1CC1)N1N=CC(C(=O)C2=CC=CC(=C2)C#N)=C1N

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