background


Product Information:

ACT-1004-1239

ACT-1004-1239 is a potent, selective, orally active CXCR7 antagonist with an IC50 value of 3.2 nM .

Cat. No.: EX-A15103    Purity: >98%
Chemical
Chemical structure of ACT-1004-1239


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg1198In-stock
100mg1798In-stock
250mg3298In-stock
500mg5698In-stock
1g7998In-stock


CAS No.2178049-58-4
Purity>98%
FormulaC27H28F2N6O3
Mol Weight522.5464
ColorWhite to off-white
StateSolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃, 3 years; 4℃, 2 years; In solvent -20℃, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Richard-Bildstein S, et al. Discovery of the Potent, Selective, Orally Available CXCR7 Antagonist ACT-1004-1239. J Med Chem. 2020 Dec 24;63(24):15864-15882.

[2]. Pouzol L, et al. ACT-1004-1239, a first-in-class CXCR7 antagonist with both immunomodulatory and promyelinating effects for the treatment of inflammatory demyelinating diseases. FASEB J. 2021 Mar;35(3):e21431.

CoACoA of ACT-1004-1239
Smiles:O=C([C@H]1CN(CC2CC2)CC[C@@H]1NC(C3=NOC(C4=CC=C(F)C=C4F)=C3)=O)NC5(C6=NC=CC=N6)CC5

KEYWORDS: buy ACT-1004-1239 | ACT-1004-1239 supplier | purchase | cost | manufacturer | order | distributor | buy 2178049-58-4 | 2178049-58-4 supplier