ACP-103

Pimavanserin is a potent 5-hydroxytryptamine (5-HT)2A receptor inverse agonist, displays potent inverse agonist activity in the cell-based functional assay receptor selection and amplification technology (R-SAT), with a mean pIC50 of 8.7.


Cat. No.: EX-A4895	Purity: 98+%

	Chemical structure of ACP-103

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	400	In-stock
500mg	550	In-stock
1g	750	In-stock
5g	1785	In-stock
10g	2685	In-stock

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Synonyms	Pimavanserin free base
CAS No.	706779-91-1
Purity	98+%
Formula	C25H34FN3O2
Mol Weight	427.5548
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Vanover KE, et al. Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist. J Pharmacol Exp Ther. 2006 May;317(2):910-8. [2]. Vanover KE, et al. A 5-HT2A receptor inverse agonist, ACP-103, reduces tremor in a rat model and levodopa-induced dyskinesias in a monkey model. Pharmacol Biochem Behav. 2008 Oct;90(4):540-4.
CoA	CoA of ACP-103

Smiles:	CC(C)COC1=CC=C(C=C1)CNC(=O)N(CC2=CC=C(C=C2)F)C3CCN(CC3)C


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