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Product Information:

ACE-083

ACE-083 is a Locally acting muscle-promoting agent

Cat. No.: EX-A10168    Purity: >99% by HPLC
Chemical
Chemical structure of ACE-083


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
1g485In-stock
5g1300In-stock
10g2000In-stock
25g3900In-stock


CAS No.81080-10-6
Purity>99% by HPLC
FormulaC20H31N3O2
Mol Weight345.479
Statesolid
Solubilitysoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃ 2 years, protect from light; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Statland, Jeffrey M et al. “Randomized phase 2 study of ACE-083, a muscle-promoting agent, in facioscapulohumeral muscular dystrophy.” Muscle & nerve vol. 66,1 (2022): 50-62. doi:10.1002/mus.27558

[2]. Thomas, Florian P et al. “Randomized Phase 2 Study of ACE-083 in Patients With Charcot-Marie-Tooth Disease.” Neurology vol. 98,23 e2356-e2367. 6 Jun. 2022, doi:10.1212/WNL.0000000000200325

[3]. Glasser, Chad E et al. “Locally acting ACE-083 increases muscle volume in healthy volunteers.” Muscle & nerve vol. 57,6 (2018): 921-926. doi:10.1002/mus.26113

[4]. Pearsall, R S et al. “Follistatin-based ligand trap ACE-083 induces localized hypertrophy of skeletal muscle with functional improvement in models of neuromuscular disease.” Scientific reports vol. 9,1 11392. 6 Aug. 2019, doi:10.1038/s41598-019-47818-w

CoACoA of ACE-083
Smiles:O=C(NC=1C=C(C(O)=C(C1)CN2CCCCC2)CN3CCCCC3)C

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