AC1-IN-1

AC1-IN-1 is a potent and selective Adenylyl cyclase type 1 (AC1) inhibitor with an IC50 of 0.54 µM. AC1-IN-1 displays modest antiallodynic effects in a mouse model of inflammatory pain. AC1-IN-1 has CNS activity.


Cat. No.: EX-A6596	Purity: >98%

	Chemical structure of AC1-IN-1

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5mg	385	In-stock
10mg	585	In-stock
25mg	785	In-stock
50mg	1185	In-stock
100mg	1650	In-stock
200mg	2385	In-stock

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CAS No.	2762422-55-7
Purity	>98%
Formula	C18H18FN5O2
Mol Weight	355.3662
Color	White to off-white
State	solid powder
Solubility	Soluble in DMSO 25 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	p>[1]. Scott JA, et al. Optimization of a Pyrimidinone Series for Selective Inhibition of Ca2+/Calmodulin-Stimulated Adenylyl Cyclase 1 Activity for the Treatment of Chronic Pain. J Med Chem. 2022; 65(6):4667-4686.
CoA	CoA of AC1-IN-1


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