Ac-RA-7-2

Ac-RFAAKAA-COOH is a cysteine-containing polypeptide with a reactive lysine residue, and serves as a substrate for covalent modification and chemical reactivity assays. Ac-RFAAKAA-COOH forms stable covalent adducts with isothiocyanates, resulting in peptide depletion over time. Ac-RFAAKAA-COOH acts as a model peptide in direct peptide reactivity assays, where its chemical reactivity is evaluated via fluorescamine-based free amine assays. Ac-RFAAKAA-COOH can be used in studies related to allergic contact dermatitis and skin sensitization.


Cat. No.: EX-A13999	Purity: >98%

	Chemical structure of Ac-RA-7-2

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
1g	680	In-stock
2g	1180	In-stock
5g	2080	In-stock

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CAS No.	845727-63-1
Purity	>98%
Formula	C35H57N11O9
Mol Weight	775.8954
Color	White to off-white
State	Solid
Solubility	H2O : 50 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -80°C, 2 years , -20°C, 1 year, sealed storage, away from moisture; In solvent -20°C, 1 month.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Karlsson I, et al. Peptide Reactivity of Isothiocyanates--Implications for Skin Allergy. Sci Rep. 2016;6:21203. Published 2016 Feb 17. [2]. Cho SA, et al. Method for detecting the reactivity of chemicals towards peptides as an alternative test method for assessing skin sensitization potential. Toxicol Lett. 2014;225(1):185-191.
CoA	CoA of Ac-RA-7-2

Smiles:	[C@@H](CC1=CC=CC=C1)(NC([C@H](CCCNC(=N)N)NC(C)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)C)=O)CCCCN)=O)C)=O)C)=O


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