Ac-DEVD-CMK TFA

Ac-DEVD-CMK TFA (Caspase-3 Inhibitor III TFA) is a selective and irreversible caspase-3 inhibitor. Ac-DEVD-CMK significantly inhibits apoptosis induced by high levels of glucose or 3,20-dibenzoate (IDB; HY-137295). Ac-DEVD-CMK can be used in a variety of experimental approaches to inhibit apoptosis.


Cat. No.: EX-A8701	Purity: >98%

	Chemical structure of Ac-DEVD-CMK TFA

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	985	In-stock
100mg	1550	In-stock
250mg	2450	In-stock
500mg	get quote	Inquire
1g	get quote	Inquire

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Synonyms	Caspase-3 Inhibitor III TFA
Purity	>98%
Formula	C23H32ClF3N4O13
Mol Weight	664.967
State	solid powder

Reference:	[1]. Eon Jeong Nam, et al. Syndecan-1 limits the progression of liver injury and promotes liver repair in acetaminophen-induced liver injury in mice. Hepatology. 2017 Nov;66(5):1601-1615. [2]. Eon Jeong Nam, et al. Syndecan-1 limits the progression of liver injury and promotes liver repair in acetaminophen-induced liver injury in mice. Hepatology. 2017 Nov;66(5):1601-1615. [3]. Nam EJ, et al. Syndecan-1 limits the progression of liver injury and promotes liver repair in acetaminophen-induced liver injury in mice. Hepatology. 2017 Nov;66(5):1601-1615. [4]. Hung KC, et al. Citrate-Induced p85α⁻PTEN Complex Formation Causes G2/M Phase Arrest in Human Pharyngeal Squamous Carcinoma Cell Lines. Int J Mol Sci. 2019 Apr 29;20(9):2105. [5]. M M Mocanu, et al. Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion injury. Br J Pharmacol. 2000 May;130(2):197-200. [6]. M Blanco-Molina, et al. Ingenol esters induce apoptosis in Jurkat cells through an AP-1 and NF-kappaB independent pathway. Chem Biol. 2001 Aug;8(8):767-78. [7]. Lu Cai, et al. Hyperglycemia-induced apoptosis in mouse myocardium: mitochondrial cytochrome C-mediated caspase-3 activation pathway. Diabetes. 2002 Jun;51(6):1938-48.
CoA	CoA of Ac-DEVD-CMK TFA


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