background


Product Information:

AC-264613

AC-264613 is a potent and selective protease-activated receptor (PAR-2) agonist with a pEC50 of 7.5[1].

Cat. No.: EX-A14519    Purity: >98%
Chemical
Chemical structure of AC-264613


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg1470Inquire
500mg2150Inquire
1g3125Inquire


CAS No.1051487-82-1
Purity>98%
FormulaC19H18BrN3O2
Mol Weight400.269
ColorWhite to off-white
StateSolid
Solubilitysoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20°C, sealed storage, away from moisture; In solvent -20°C, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Jimmi Gerner Seitzberg, et al. Discovery of potent and selective small-molecule PAR-2 agonists. J Med Chem. 2008 Sep 25;51(18):5490-3.

[2]. Rui Yamaguchi, et al. A protease-activated receptor 2 agonist (AC-264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macrophages: Role of p53. Cell Biol Int. 2016 Jun;40(6):629-41

[3]. Luis R Gardell, et al. Identification and characterization of novel small-molecule protease-activated receptor 2 agonists. J Pharmacol Exp Ther. 2008 Dec;327(3):799-808.

CoACoA of AC-264613
Smiles:C/C(=N\NC(=O)[C@@H]1[C@H](CNC1=O)C2=CC=CC=C2)/C3=CC(=CC=C3)Br

KEYWORDS: buy AC-264613 | AC-264613 supplier | purchase | cost | manufacturer | order | distributor | buy 1051487-82-1 | 1051487-82-1 supplier