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Product Information:

ABX-1431

ABX-1431 is a highly potent, selective, and orally available, CNS-penetrant monoacylglycerol lipase (MAGL) inhibitor with an IC50 of 14 nM.

Cat. No.: EX-A2760    Purity: >98%
Chemical
Chemical structure of ABX-1431


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg570In-stock
500mg950In-stock
1g1350In-stock


CAS No.1446817-84-0
Purity>98%
FormulaC20H22F9N3O2
Mol Weight507.3932
Colorwhite to off-white
Statepowder
SolubilityDMSO >100 mg/mL; Insoluble in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Cisar JS, et al. Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders. J Med Chem. 2018 Oct 25;61(20):9062-9084.
CoACoA of ABX-1431
Smiles:FC(F)(F)C(OC(=O)N1CCN(CC2=C(C=C(C=C2)C(F)(F)F)N2CCCC2)CC1)C(F)(F)F

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