ABT-102

ABT-102 is a potent and highly selective Vanilloid Receptor (TRPV1) receptor antagonist. ABT-102 potently and reversibly increases heat pain thresholds and reduced painfulness of suprathreshold oral/cutaneous heat. ABT-102 reduces nociceptive responses of animals in models of inflammatory, bone cancer, postoperative, and osteoarthritic pain .


Cat. No.: EX-A12463	Purity: >98%

	Chemical structure of ABT-102

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	400	In-stock
25g	800	In-stock
50g	1250	In-stock
100g	2040	In-stock
250	4050	In-stock
500	6500	In-stock

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


CAS No.	808756-71-0
Purity	>98%
Formula	C21H24N4O
Mol Weight	348.4415
State	solid powder
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, sealed storage, away from moisture, 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Lukin K, et al. Development of a Large Scale Asymmetric Synthesis of Vanilloid Receptor (TRPV1) Antagonist ABT-102. Organic Process Research & Development, 2007, 11(3):578-584. [2]. Rowbotham MC, et al. Oral and cutaneous thermosensory profile of selective TRPV1 inhibition by ABT-102 in a randomized healthy volunteer trial. Pain. 2011 May;152(5):1192-1200.
CoA	CoA of ABT-102

Smiles:	O=C(NC1=CC=CC2=C1C=NN2)N[C@@H]3CCC4=C3C=CC(C(C)(C)C)=C4


		Search