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Product Information:

ABBV-744

ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2, BRD3 and BRD4. It is developed for treating AML and cancers.

Cat. No.: EX-A2713    Purity: >98%
Chemical
Chemical structure of ABBV-744


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg880In-stock
500mg1250In-stock
1g1850In-stock
5g6685In-stock
10g9985In-stock


CAS No.2138861-99-9
Purity>98%
FormulaC28H30FN3O4
Mol Weight491.5539
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1] Emily J. Faivre, et al. First-in-class, highly BDII-selective BET family inhibitor ABBV-744 displays potent anti-tumor activity in androgen receptor positive prostate cancer models and an improved tolerability profile. AACR; Cancer Res. 2018, 78(13 Suppl):Abstract nr 4960.
CoACoA of ABBV-744
Smiles:CCNC(=O)C1=CC2=C(N1)C(=O)N(C)C=C2C1=C(OC2=C(C)C=C(F)C=C2C)C=CC(=C1)C(C)(C)O

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