Aβ-IN-3

Aβ-IN-3 (compound 1) is a potent amyloid β (Aβ) inhibitor. Aβ-IN-3 inhibits Aβ42 aggregation. However, Aβ-IN-3 can not alleviate the neurotoxicity of Aβ42 in SH-SY5Y cells. Aβ-IN-3 can not change the aggregation state of Aβ42 into a nontoxic one .


Cat. No.: EX-A15759	Purity: >98%

	Chemical structure of Aβ-IN-3

For research only, Do not use for Human!

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CAS No.	2477606-87-2
Purity	>98%
Formula	C33H43N5O7
Mol Weight	621.7238
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Tanaka F, et al. Design and synthesis of β-strand-fixed peptides inhibiting aggregation of amyloid β-protein. Bioorg Med Chem. 2020 Sep 15;28(18):115676.
CoA	CoA of Aβ-IN-3

Smiles:	C([C@@H]1NC(=O)[C@@H](NC([C@H](CC(C)C)N)=O)CC=2C=CC(=CC2)OC\C=C\C[C@@H](C(N[C@H](C(O)=O)C)=O)NC1=O)C3=CC=CC=C3


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