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Product Information:

AB-729

AB-729, a nucleoside analogue, is a RNA interference (RNAi). AB-729 conjugates to a trimer of N-acetylgalactosamine (GalNAc) ligand that promotes uptake into hepatocytes via the asialoglycoprotein receptor (ASGR). AB-729 inhibits viral replication and reduces HBV antigens.

Cat. No.: EX-A7153    Purity: >98%
Chemical
Chemical structure of AB-729


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
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10mg2250Inquire
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SynonymssiRNA AB-729
Synonyms 2Pharmaceutical siRNA AB-729
CAS No.2634739-74-3
Purity>98%
Shelf Life>2 years if stored properly
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Efthymios P Tsounis, et al. Toward a new era of hepatitis B virus therapeutics: The pursuit of a functional cure. World J Gastroenterol. 2021 Jun 7;27(21):2727-2757.

[2]. Arbutus Receives Authorization to Proceed with an Investigational New Drug Application (IND) for AB-729, its Proprietary Subcutaneously-Delivered RNAi Agent.

CoACoA of AB-729

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