A1899

A1899 is a potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) channel blocker (IC50 values are 7 nM and 70 nM for human TASK-1 and TASK-3 expressed in CHO cells, respectively).


Cat. No.: EX-A5109	Purity: >98%

	Chemical structure of A1899

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	950	Inquire
250mg	1550
1g	2850	Inquire
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CAS No.	498577-46-1
Purity	>98%
Formula	C30H26F2N2O3
Mol Weight	500.5358
Color	Off-white to light yellow
State	solid powder
Solubility	Soluble in DMSO 125 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Streit AK, et al. A specific two-pore domain potassium channel blocker defines the structure of the TASK-1 open pore. J Biol Chem. 2011 Apr 22;286(16):13977-84. doi: 10.1074/jbc.M111.227884. Epub 2011 Mar 1. PubMed PMID: 21362619; PubMed Central PMCID: PMC3077598.
CoA	CoA of A1899

Smiles:	O=C(C1=CC=CC=C1C2=CC=CC=C2CNC(CC3=CC=C(OC)C=C3)=O)NCC4=CC=C(F)C=C4F


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