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Product Information:

α-Glucosidase-IN-92

α-Glucosidase-IN-92 (compound 14b) is a non-competitive inhibitor targeting α-glucosidase (IC50=64.0 μM), with better inhibitory potency than Acarbose (IC50=750 μM). α-Glucosidase-IN-92 has good oral bioavailability and can cross the blood-brain barrier. α-Glucosidase-IN-92 can delay carbohydrate hydrolysis and reduce postprandial blood glucose. α-Glucosidase-IN-92 can be used in anti-glycemic research for type 2 diabetes.

Cat. No.: EX-A13312    Purity: >98%
Chemical
Chemical structure of α-Glucosidase-IN-92


For research only, Do not use for Human!

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Synonymsalpha-Glucosidase-IN-92
Purity>98%
FormulaC30H25N7O2
Mol Weight515.5652
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Safaie E, et al. 1-Phenyl-β-carboline-3-carboxamide-1,2,3-triazole-N-phenylacetamide hybrids as new α-glucosidase inhibitors. Sci Rep. 2025 May 20;15(1):17418.

CoACoA of α-Glucosidase-IN-92
Smiles:O=C(C1=CC2=C(C(C3=CC=CC=C3)=N1)NC4=C2C=CC=C4)NCC5=CN(CC(NC6=CC=CC=C6C)=O)N=N5

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