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Product Information:

α-Amylase-IN-12

α-Amylase-IN-12 (Compound 5e) is an α-amylase inhibitor (IC50: 0.15 mM) with a mixed inhibition. α-Amylase-IN-12 has an IC50 of 9.40 mM against α-glucosidase. α-Amylase-IN-12 promotes glucose uptake in yeast cells and exhibits significant antiglycation activity at high concentrations. α-Amylase-IN-12 can be used for the research of diabetes.

Cat. No.: EX-A12131    Purity: >98%
Chemical
Chemical structure of α-Amylase-IN-12


For research only, Do not use for Human!

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CAS No.1799667-33-6
Purity>98%
FormulaC16H11NO4
Mol Weight281.2628
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Jayasinghe R N, et al. Evaluation of In Silico and In Vitro Antidiabetic Properties of 4-(Hydroxysubstituted Arylidene)-2-Phenyloxazol-5 (4 H)-one Derivatives. ACS Omega, 2025.

CoACoA of α-Amylase-IN-12
Smiles:C(=C/1\N=C(OC1=O)C2=CC=CC=C2)\C3=CC(O)=C(O)C=C3

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