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Product Information:

A-443654

A-443654 is a pan-Akt inhibitor and has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).

Cat. No.: EX-A7113    Purity: >98%
Chemical
Chemical structure of A-443654


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg685In-stock
50mg985In-stock
100mg1485In-stock
200mg2285In-stock


CAS No.552325-16-3
Purity>98%
FormulaC24H23N5O
Mol Weight397.4723
Color White to off-white
Statesolid powder
SolubilitySoluble in DMSO? 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years; 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Luo Y, et al. Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo. Mol Cancer Ther. 2005 Jun;4(6):977-86.

[2]. Zheng J, et al. Rapamycin sensitizes Akt inhibition in malignant human breast epithelial cells. Cancer Lett. 2010 Oct 1;296(1):74-87.

CoACoA of A-443654

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