A-1210477

A-1210477 is a potent and selective inhibitor of MCL-1 with a Ki of 0.45 nM. A-1210477 specifically binds MCL-1 and promotes apoptosis of cancer cells in an MCL-1-dependent manner.


Cat. No.: EX-A1582	Purity: >98%

	Chemical structure of A-1210477

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	532	in_stock
500mg	792	in_stock
1g	1295	in_stock
5g	4113	in_stock
10g	6113	in_stock

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CAS No.	1668553-26-1
Purity	>98%
Formula	C46H55N7O7S
Mol Weight	850.037
Color	white to off-white
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Yuda J, et al. Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients. Commun Med (Lond). 2023 Oct 25;3(1):154.
CoA	CoA of A-1210477

Smiles:	CN(C)S(=O)(=O)N1CCN(CC1)C1=CC=C(OCC2=C(C(C)=NN2C)C2=CC=CC3=C2N(CCN2CCOCC2)C(C(O)=O)=C3CCCOC2=C3C=CC=CC3=CC=C2)C=C1


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